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SIBS Syllabus

A tenative syllabus for Summer 2018 based on the 2017 syllabus is shown below; the 2017 events are mapped to the 2018 dates for the program (June 10 - July 20, 2018). The actual syllabus is still being finalized but will be similar.

On most days (Mon-Fri), instruction will be in the form of lectures, special presentations, and group panel discussions in a morning (AM) session from 10:00 am - noon. In the afternoon (PM) session from 1:30 pm - 3:30pm, students will engage in "hands-on" activities including learning to use statistical software, data analyses, and computer simulation exercises.

Each week will feature a field trip related to issues of importance to biostatistics. Bus transportation will be provided.

Following common statistical practice, students will be randomized into teams of 2-3. During the first week of the program, each team will be assigned a project involving data from a real study carried out by Duke Clinical Research Institute or other research institutions. Over the course of the program, teams will become familiar with the data and, using techniques learned in class, carry out analyses to address the questions from the study. Teams will present their results during the last week of the program.

On weekends, we will take several "fun" field trips to attractions in the Triangle area and beyond. Field trips given below are representative and are subject to change.

Week 2
06/18/201810:00am - 12:00pmSample size and power
06/18/201801:30pm - 03:30pmSample size calculation in practice
06/18/201804:00pm - 05:00pmOptional Lecture: Maximum likelihood - theory and methods
06/19/201810:00am - 12:00pm@Duke - Introduction to clinical trials: Randomization, sample size, conduct of trials, and the intent-to-treat principle
06/19/201812:15pm - 01:15pmLunch - What's it like to be a grad student?
06/19/201801:30pm - 03:30pmIntroduction to clinical trials, continued.
06/20/201810:00am - 12:00pmWhen should a clinical trial be stopped? Introduction to early stopping and monitoring of clinical trials
06/20/201801:30pm - 03:30pmDesigning a clinical trial and planning the statistical analysis
06/20/201804:00pm - 05:00pmOptional Lecture: Group sequential trials.
06/21/201810:00am - 12:00pmAssociations among variables and introduction to linear regression analysis
06/21/201801:30pm - 03:30pmUsing statistical software for estimating associations and regression analysis
06/22/201810:00am - 12:00pm@Duke - From lab to patient : Statistics in drug development
06/22/201801:30pm - 04:30pmField Trip to Quintiles
06/23/2018All DayTrip to Defy Gravity

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